Eleutherococcus senticosus (root bark)

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Eleuthero (root bark) (Eleutherococcus senticosus)

General Characteristics Not reported.

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Eleuthero (root bark) (Eleutherococcus senticosus) 

General Characteristics AHPA recommends in its Known Adulterants list that appropriate steps be taken to assure that this raw material is free of the noted adulterant. Contact AHPA for additional information regarding relevant analytical methods or follow this link for more information. 

Reported Adulterants Periploca sepium root.

Source: AHPA Known Adulterants ^[1]

AHPA Practical: Identification and Quality Control of Eleuthero (Eleutherococcus senticosus) root

Introduction

Neonatal androgenization was associated with the ingestion of a product during pregnancy, which was labeled as containing Siberian ginseng (1). The image on the product was of an actual ginseng plant (Panax spp.) not Eleutherococcus senticosus (formerly sometimes referred to as Siberian ginseng) and analysis of the product indicated that neither eleuthero nor ginseng compounds were present, but that Chinese silk vine (Periploca sepium) was (2).

Methods of Analysis

Quality control of roots of Eleutherococcus senticosus by HPLC

Identification method of Eleuthero senticosus by HPTLC

References

1. Koren G et al. Maternal ginseng use associated with neonatal androgenization. Journal of the American Medical Association, 1990, 264:1866.
2. Awang DV. Maternal use of ginseng and neonatal androgenization. Journal of the American Medical Association, 1991, 264:2865.

Additional Information

Awang D. Siberian ginseng toxicity may be case of mistaken identity. CMAJ. 1996 Nov 1;155(9):1237.

Waller DP et al. Lack of androgenicity of Siberian ginseng. Journal of the American Medical Association, 1991, 265:1826.

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